Using a mouse model of diabetic pregnancy, Salbaum et al. assayed placental gene expression in diabetic placentas to investigate cellular and molecular alterations linked to compromised placental function in gestational diabetes. Diabetes was induced in 7- to 9-week-old FVB female mice by two intraperitoneal injections of streptozotocin. Placentas were dissected from FVB dams under diabetic conditions and untreated controls at embryonic day 10.5.

Tissue Condition Samples
Test placenta diabetic pregnancy 5
Control placenta normal pregnancy 5
Gene Fold Change (log2) Significance Genus Species