Tattersall et al. aimed to identify factors that mediate the effect of stretch on human myometrium. The study obtained myometrial samples from non-laboring patients, undergoing routine elective cesarean section at 38-40 weeks of pregnancy, for microarray analysis. Human myometrial explants were maintained in prolonged culture (65 hours) under either low tension (0.6 g) or high tension (2.4 g). Following culture, the samples were trimmed to remove tissue that had not been incubated under tension, snap frozen in liquid nitrogen, and stored at −80 °C.

Tissue Condition Samples
Test myometrium myometrium under high tension 9
Control myometrium myometrium under low tension 9
Gene Fold Change (log2) Significance Genus Species