Hui et al. investigated whether the relative representation of organ-specific transcripts in amniotic fluid cell-free fetal RNA differs between second trimester and term pregnancies. Microarray analysis was performed on amniotic fluid samples from women who underwent routine amniocenteses at 16–19 weeks of gestation and from women undergoing scheduled prelabor cesarean deliveries at 37–40 weeks of gestation.

Tissue Condition Samples
Test amniotic fluid third trimester pregnancy 8
Control amniotic fluid second trimester pregnancy 8
Gene Fold Change (log2) Significance Genus Species