Textoris et al. used microarray profiling to study the transcriptional signature of blood samples associated with preeclampsia. The study included 13 women with severe preeclampsia, 6 women with non-severe preeclampsia, and 19 women with normal pregnancies. The criteria used to define severe preeclampsia included one of the following conditions: blood pressure higher than 160/110 mmHg, proteinuria higher than 1500 mg/24 h, maternal cerebral symptoms (seizures, stroke), intrauterine growth restriction below the 3° percentile, or multisystem disorder. Blood samples were collected from participants at the time of study inclusion.

Tissue Condition Samples
Test blood severe preeclampsia 12
Control blood normal pregnancy 18
Gene Fold Change (log2) Significance Genus Species