To delineate the mechanism of PGF2α-induced luteolysis, Priyanka et al. studied the changes in global gene expression within the corpus luteum following PGF2α treatment in female bonnet monkeys. Female monkeys were treated with PGF2α or PBS (vehicle) via three injections on day 10 of the luteal phase, and corpus luteum samples were collected following 24 hours.

Tissue Condition Samples
Test corpus luteum PGF2α-treated female 3
Control corpus luteum vehicle-treated control 3
Gene Fold Change (log2) Significance Genus Species